| Cat.No.: | BSM-0221 |
| Product Name: | Sirtinol |
| CAS No.: | 410536-97-9 |
| Figure: |
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| Synonyms: | 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide; Sir Two Inhibitor Naphthol |
| Description: | Selective sirtuin inhibitor which does not effect HDAC1 (IC50 = 131 M, 38 M and 68 M for SIRT1, SIRT2 and Sir2P respectively). Induces apoptotic and autophagic cell death in MCF-7 human breast cancer cell lines. Significantly decreases growth and viability of PCa and HEK293T cells in vitro. Displays pro-inflammatory effects in adipocytes. |
| Appearance: | Yellow solid |
| Molecular Weight: | 394.47 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | SIRT |
| Molecular Formula: | C26H22N2O2 |
| MDL Number: | MFCD00810186 |
| Solubility: | DMSO (100 mM) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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