| Cat.No.: | BSM-0215 |
| Product Name: | SGC0946 |
| CAS No.: | 1561178-17-3 |
| Figure: |
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| Synonyms: | 1-[3-[[[(2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl](isopropyl)amino]propyl]-3-[4-(2,2-dimethylethyl)phenyl]urea |
| Description: | SGC0946 is a potent small-molecule inhibitor specific for protein methyltransferase DOT1L. SGC0946 also potently reduces H3K79 dimethylation with cellular IC50 of 2.6 nM in A431 cells, and 8.8 nM in MCF10A cells. |
| Appearance: | White solid |
| Molecular Weight: | 618.57 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | DOT1L |
| Molecular Formula: | C28H40BrN7O4 |
| MDL Number: | MFCD00386477 |
| Solubility: | DMSO (> 50 mg/ml) or EtOH (>50 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
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