Cat.No.: | BSM-0209 |
Product Name: | Salermide |
CAS No.: | 1105698-15-4 |
Figure: | |
Abbr: | Salermide(SIRT1, SIRT2) |
Synonyms: | N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide |
Description: | Cell-permeable. Salermide is an inhibitor of SIRT1 and SIRT2. In vitro, Salermide has a stronger inhibitory effect on SIRT2 than on SIRT1. It induces massive apoptosis in tumor cells through reactivation of proapoptotic genes epigenetically repressed exclusively in cancer cells by SIRT1. |
Appearance: | Yellow powder. |
Molecular Weight: | 394.47 |
Purity: | ≥98% |
Storage: | -20°C |
Targets: | SIRT1, SIRT2 |
Molecular Formula: | C26H22N2O2 |
MDL Number: | MFCD12912446 |
Solubility: | DMSO (100 mM) |
Shipping Conditions: | Gel Pack |
Warning: | For Research Use Only! Not For Use in Humans. |
Product Types | ||
◆ Extracts & Lysates | ||
EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
◆ Synthetic Peptides | ||
SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
Related Gene / Proteins | |||
Siah2 | SIK1 | SIMC1 | SIN3A |
SIN3B | SIP1 | Sir2p | SIRT |
SIRT1 | SIRT2 | SIRT3 | SIRT4 |
SIRT5 | sirt6 | SIRT7 | SIX3 |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools