| Cat.No.: | BSM-0207 |
| Product Name: | Ryuvidine |
| CAS No.: | 265312-55-8 |
| Figure: |
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| Synonyms: | 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione |
| Description: | Ryuvidine is a potent inhibitor of SET domain-containing protein 8 (SETD8) (IC₅₀ = 0.5 µM) that suppresses monomethylation of H4K20 in vitro. It displays weak inhibiton against cyclin-dependent kinase 4 (Cdk4; IC₅₀ = 6 µM for Cdk4/cyclin D1). Induces S phase accumulation in HEK293T cells. Cytotoxic against a range of human cancer cells. |
| Appearance: | Dark purple solid |
| Molecular Weight: | 284.33 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | SET domain-containing protein 8 (SETD8) |
| Molecular Formula: | C₁₅H₁₂N₂O₂S |
| MDL Number: | MFCD12031592 |
| Solubility: | DMSO (~5 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
| EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
| EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
| EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| SENP3 | SENP8 | SET | SET1 |
| SET2 | SET7 | SET8 | SET9 |
| SETBP1 | SETD1A | SETD1B | SETD2 |
| SETD3 | SETD5 | SETD6 | SETD7 |
| SETD8 | SETD9 | SetDB1 | SETDB2 More > |
| SETMAR | |||
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