| Cat.No.: | BSM-0202 |
| Product Name: | RG 108 |
| CAS No.: | 48208-26-0 |
| Figure: |
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| Synonyms: | RG-108, N-Phthalyl-L-tryptophan; or (S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid |
| Product Overview: | A DNA methyltransferase (DNMT) inhibitor |
| Description: | A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294, RG 108 enhances reprogramming. |
| Appearance: | Yellow solid |
| Molecular Weight: | 334.33 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | DNMT1 |
| Molecular Formula: | C19H14N2O4 |
| MDL Number: | MFCD00149487 |
| Solubility: | DMSO (10 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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