| Cat.No.: | BSM-0188 |
| Product Name: | ORY-1001 |
| CAS No.: | 1431326-61-2 |
| Figure: |
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| Synonyms: | N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine, dihydrochloride; RG-6016 |
| Description: | ORY-1001 is a potent and selective inhibitor of LSD1 (IC₅₀ < 20 nM). It targets acute myeloid leukemia (AML) stem cells and significantly reduces tumor cell load while increasing survival time in mouse models of AML. ORY-1001 is in clinical trials for cancer treatment. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 303.27 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | LSD1 |
| Molecular Formula: | C₁₅H₂₄Cl₂N₂ |
| MDL Number: | MFCD08705329 |
| Solubility: | DMSO (~7 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0062 | Histone Demethylase LSD1 Activity/Inhibition Assay Kit | Inquiry |
| EKIT-0126 | LSD1 Inhibitor Screening Assay Kit | Inquiry |
| EKIT-0160 | LSD1 Demethylase Activity/Inhibition Fluorometric Assay Kit | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0111 | DDP-38003 dihydrochloride | Inquiry |
| BSM-0141 | GSK-LSD1 dihydrochloride | Inquiry |
| Related Gene / Proteins | |||
| LSD1 | LSD2 | LSM2 | LSM3 |
| LSM5 | LSM6 | LSP1 | |
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