| Cat.No.: | BSM-0187 |
| Product Name: | OICR-9429 |
| CAS No.: | 1801787-56-3 |
| Figure: |
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| Synonyms: | N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4- ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide |
| Description: | OICR-9429 is a small-molecule inhibitor of the WDR5-MLL interaction that effectively stops the growth of breast cancer cell lines driven by p53 gene mutation. It also stops the growth of subtype of leukemia cells having specific mutation found in about 9% of the patients with acute myeloid leukemia. WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. |
| Appearance: | Yellow solid |
| Molecular Weight: | 555.59 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | WDR5-MLL interaction |
| Molecular Formula: | C₂₉H₃₂F₃N₅O₃ |
| MDL Number: | MFCD08705329 |
| Solubility: | DMSO (>25 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0005 | WDR5 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0052 | Recombinant Human WDTC1 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0170 | MI-3 | Inquiry |
| BSM-0187 | OICR-9429 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0172 | Human KMT2C / MLL3 peptide | Inquiry |
| Related Gene / Proteins | |||
| MLH1 | MLL | mll1 | MLL2 |
| MLL3 | MLL4 | MLL5 | MLLT1 |
| MLLT3 | WDHD1 | WDR4 | WDR5 |
| WDR77 | WDR82 | WDTC1 | |
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