| Cat.No.: | BSM-0178 |
| Product Name: | Nanaomycin A |
| CAS No.: | 52934-83-5 |
| Figure: |
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| Synonyms: | 2-[(1S, 3R)-9-hydroxy-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-3-yl]acetic acid; Nanafrocin, Nanafrocine, Nanafrocinum, Rosanomycin A |
| Description: | Nanaomycin A is a selective DNA methyltransferase 3B (DNMT3B) inhibitor. It induces antiproliferative effects in three different tumor cell lines originating from different tissues. Nanaomycin A treatment reduces the global methylation levels in all three cell lines and reactivates transcription of the RASSF1A tumor suppressor gene. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 302.28 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | DNA methyltransferase 3B (DNMT3B) |
| Molecular Formula: | C₁₆H₁₄O₆ |
| MDL Number: | MFCD00913253 |
| Solubility: | DMSO (~10 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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