| Cat.No.: | BSM-0162 |
| Product Name: | LDN-57444 |
| CAS No.: | 668467-91-2 |
| Figure: |
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| Synonyms: | 3-(O-acetyloxime), 5-chloro-1-[(2,5-dichlorophenyl)methyl]-1H-Indole-2,3-dione, C30, LDN 57444 |
| Description: | Cell-permeable. LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1 (Ki = 0.4 μM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. |
| Appearance: | Yellow solid |
| Molecular Weight: | 397.64 |
| Purity: | ≥98% by TLC |
| Storage: | -20°C |
| Targets: | UCHL1 |
| Molecular Formula: | C₁₇H₁₁Cl₃N₂O₃ |
| MDL Number: | MFCD09037562 |
| Solubility: | DMSO (20 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0162 | LDN-57444 | Inquiry |
| BSM-0184 | NSC-687852 | Inquiry |
| BSM-0233 | TCID | Inquiry |
| ◆ Cell Lines | ||
| CL-0291 | Human UCHL1 Knockout Cell Line 11bp deletion | Inquiry |
| CL-0296 | Human UCHL3 Knockout Cell Line 11bp deletion | Inquiry |
| Related Gene / Proteins | |||
| UCHL1 | UCHL3 | UCHL5 | |
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