| Cat.No.: | BSM-0152 |
| Product Name: | IOX1 |
| CAS No.: | 5852-78-8 |
| Figure: |
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| Synonyms: | IOX-1, 8-Hydroxy-5-quinolinecarboxylic acid; 5-Carboxy-8HQ |
| Description: | Cell-permeable. A histone demethylase (HDM) JMJD nhibitor. Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6 and 1 M for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling. Cell permeable. |
| Appearance: | Yellow solid |
| Molecular Weight: | 189.17 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | Demethylase JMJD |
| Molecular Formula: | C10H7NO3 |
| MDL Number: | MFCD18417145 |
| Solubility: | DMSO (>20 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0072 | JMJD6 Polyclonal Antibody | Inquiry |
| EAb-0074 | JMJD2c Polyclonal Antibody | Inquiry |
| EAb-0075 | JMJD2b Polyclonal Antibody | Inquiry |
| EAb-0076 | JMJD2A Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JMJD | JMJD1A | JMJD1B | JMJD1C |
| JMJD2 | JMJD2A | JMJD2B | JMJD2C |
| JMJD2D | JMJD2E | JMJD2F | JMJD3 |
| JMJD4 | JMJD5 | JMJD6 | |
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