| Cat.No.: | BSM-0141 |
| Product Name: | GSK-LSD1 dihydrochloride |
| CAS No.: | 1431368-48-7 (free base) |
| Figure: |
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| Synonyms: | N-((1R,2S)-2-phenylcyclopropyl)piperidin-4-amine dihydrochloride |
| Description: | GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 2HCl irreversibly inhibits LSD1 with IC₅₀ value of 16 nM and is > 1000 fold selective over LSD2, MAO-A and MAO-B, which were related to FAD utilizing enzymes. GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns. |
| Appearance: | White to off-white solid |
| Molecular Weight: | 289.24 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | Lysine specific demethylase 1 (LSD1) |
| Molecular Formula: | C14H22Cl2N2 |
| MDL Number: | MFCD22683852 |
| Solubility: | H₂O (>20 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0062 | Histone Demethylase LSD1 Activity/Inhibition Assay Kit | Inquiry |
| EKIT-0126 | LSD1 Inhibitor Screening Assay Kit | Inquiry |
| EKIT-0160 | LSD1 Demethylase Activity/Inhibition Fluorometric Assay Kit | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0111 | DDP-38003 dihydrochloride | Inquiry |
| BSM-0141 | GSK-LSD1 dihydrochloride | Inquiry |
| Related Gene / Proteins | |||
| LSD1 | LSD2 | LSM2 | LSM3 |
| LSM5 | LSM6 | LSP1 | |
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