Cat.No.: | BSM-0132 |
Product Name: | Romidepsin (FK228, depsipeptide) |
CAS No.: | 128517-07-7 |
Figure: | |
Synonyms: | Romidepsin, FK228, FK 228, FR901228, Depsipeptide |
Description: | A natural prodrug that inhibits Class I histone deacetylases (HDACs) (IC50 values are: 36, 47, 510 and 14000 nM for HDAC1, HDAC2, HDAC4 and HDAC6, respectively). Besides HDAC inhibition, romidepsin is also able to induce cell cycle arrest, cellular differentiation, apoptosis and alteration of gene expression in adult malignancies. |
Appearance: | White solid |
Molecular Weight: | 540.7 |
Purity: | ≥98% by HPLC |
Storage: | -20°C |
Targets: | Class I HDAC |
Molecular Formula: | C24H36N4O6S2 |
MDL Number: | MFCD03848392 |
Solubility: | DMSO (~ 5 mg/ml) |
Shipping Conditions: | Gel Pack |
Warning: | For Research Use Only! Not For Use in Humans. |
Product Types | ||
◆ Extracts & Lysates | ||
EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
◆ Bioactive Small Molecules | ||
BSM-0007 | Tubacin | Inquiry |
Related Gene / Proteins | |||
HDAC | HDAC1 | HDAC10 | HDAC11 |
HDAC2 | HDAC3 | hdac4 | hdac5 |
HDAC6 | hdac7 | HDAC8 | hdac9 |
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