Romidepsin (FK228, depsipeptide)


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Cat.No.:  BSM-0132
Product Name:  Romidepsin (FK228, depsipeptide)
CAS No.:  128517-07-7
Figure: 
Synonyms:  Romidepsin, FK228, FK 228, FR901228, Depsipeptide
Description:  A natural prodrug that inhibits Class I histone deacetylases (HDACs) (IC50 values are: 36, 47, 510 and 14000 nM for HDAC1, HDAC2, HDAC4 and HDAC6, respectively). Besides HDAC inhibition, romidepsin is also able to induce cell cycle arrest, cellular differentiation, apoptosis and alteration of gene expression in adult malignancies.
Appearance:  White solid
Molecular Weight:  540.7
Purity:  ≥98% by HPLC
Storage:  -20°C
Targets:  Class I HDAC
Molecular Formula:  C24H36N4O6S2
MDL Number:  MFCD03848392
Solubility:  DMSO (~ 5 mg/ml)
Shipping Conditions:  Gel Pack
Warning:  For Research Use Only! Not For Use in Humans.

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