| Cat.No.: | BSM-0119 |
| Product Name: | Ebselen |
| CAS No.: | 60940-34-3 |
| Figure: |
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| Synonyms: | 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one |
| Description: | An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC₅₀ of 5.17 µM. |
| Appearance: | White to off-white solid |
| Molecular Weight: | 274.18 |
| Purity: | ≥99% |
| Storage: | -20°C |
| Targets: | Histone-lysine demethylase (HKDM) |
| Molecular Formula: | C₁₃H₉NOSe |
| MDL Number: | MFCD00210937 |
| Solubility: | DMSO (~ 5 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0002 | AT9283 | Inquiry |
| ◆ Cell Lines | ||
| CL-0017 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| CL-0081 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0079 | JARID2 Polyclonal Antibody | Inquiry |
| EAb-0080 | JARID1C Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JADE1 | JAK | JAK1 | JAK2 |
| JAK3 | JAKMIP1 | JARID | JARID1 |
| JARID1A | JARID1B | JARID1C | JARID2 |
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