| Cat.No.: | BSM-0115 |
| Product Name: | DNA methylation inhibitor, Dichlone |
| CAS No.: | 117-80-6 |
| Figure: |
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| Synonyms: | 2,3-Dichloro-1,4-naphthoquinone, Dichlon |
| Description: | Dichlone, a popular pesticide and fungicide, acts as a potent DNA methylation inhibitor (EC₅₀ = 460 nM against Dnmt3A/3L catalytic complex). Dichlone efficiently reactivates YFP gene expression in a stable HEK293 cell line by promoter demethylation. |
| Appearance: | Yellow solid |
| Molecular Weight: | 227.04 |
| Purity: | ≥95% by GC |
| Storage: | -20°C |
| Targets: | DNA methylation |
| Molecular Formula: | C₁₀H₄Cl₂O₂ |
| MDL Number: | MFCD00001677 |
| Solubility: | DMSO or EtOH |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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