| Cat.No.: | BSM-0113 |
| Product Name: | Disulfiram |
| CAS No.: | 97-77-8 |
| Figure: |
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| Synonyms: | 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane;Tetraethylthiuram disulfide; is(diethylthiocarbamyoyl)disulfide |
| Description: | An alcohol dehydrogenase inhibitor used for the treatment of chronic alcoholism. Suppresses the invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression. Also inhibits JMJD2A, a 2-oxoglutarate dependent N(epsilon)-methyl lysine histone demethylase, by disruption of its Zn-binding site. |
| Appearance: | Pale yellow solid |
| Molecular Weight: | 296.54 |
| Purity: | ≥97% by titration |
| Storage: | -20 ̊C |
| Targets: | JMJD2A |
| Molecular Formula: | C₁₀H₂₀N₂S₄ |
| MDL Number: | MCFD00009048 |
| Solubility: | DMSO (~ 6 mg/ml) or Ethanol (~ 30 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0072 | JMJD6 Polyclonal Antibody | Inquiry |
| EAb-0074 | JMJD2c Polyclonal Antibody | Inquiry |
| EAb-0075 | JMJD2b Polyclonal Antibody | Inquiry |
| EAb-0076 | JMJD2A Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JMJD | JMJD1A | JMJD1B | JMJD1C |
| JMJD2 | JMJD2A | JMJD2B | JMJD2C |
| JMJD2D | JMJD2E | JMJD2F | JMJD3 |
| JMJD4 | JMJD5 | JMJD6 | |
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