| Cat.No.: | BSM-0109 |
| Product Name: | Cyt387 |
| CAS No.: | 1056634-68-4 |
| Figure: |
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| Synonyms: | (N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-l)-benzamide; CYT11387 |
| Description: | Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ values of 11 nM and 18 nM, respectively. Inhibits JAK3 at much higher concentrations (IC₅₀ = 155 nM). |
| Appearance: | Yellow to light orange solid |
| Molecular Weight: | 414.46 |
| Purity: | ≥98% by HPLC |
| Storage: | -20 ̊C |
| Targets: | JAK1 and JAK2 |
| Molecular Formula: | C₂₃H₂₂N₆O₂ |
| MDL Number: | MFCD16038899 |
| Solubility: | DMSO (~80 mg/ml) or Ethanol (<1 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0002 | AT9283 | Inquiry |
| ◆ Cell Lines | ||
| CL-0017 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| CL-0081 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0079 | JARID2 Polyclonal Antibody | Inquiry |
| EAb-0080 | JARID1C Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JADE1 | JAK | JAK1 | JAK2 |
| JAK3 | JAKMIP1 | JARID | JARID1 |
| JARID1A | JARID1B | JARID1C | JARID2 |
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