| Cat.No.: | BSM-0108 |
| Product Name: | Curcumin, Curcuma longa (High Purity) |
| CAS No.: | 458-37-7 |
| Figure: |
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| Synonyms: | 1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane |
| Description: | Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (COX) (IC₅₀ = 52 µM). Also inhibits glutathione S-transferase, induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an IC₅₀ of ~25 µM. Does not affect p300/CREB binding protein-associated factor (PCAF). |
| Appearance: | Orange-yellow solid |
| Molecular Weight: | 368.38 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | Histone acetyltransferase |
| Molecular Formula: | C₂₁H₂₀O₆ |
| MDL Number: | MFCD00008365 |
| Solubility: | DMSO (25 mg/ml) or EtOH (10 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0038 | CTPB | Inquiry |
| BSM-0039 | Embelin | Inquiry |
| BSM-0073 | Anacardic Acid | Inquiry |
| ◆ Antibodies | ||
| EAb-0060 | PCAF Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0061 | Human EP300 Knockout Cell Line 13bp deletion | Inquiry |
| Related Gene / Proteins | |||
| EP300 | EPC1 | PCAF | PCBP2 |
| PCBP3 | PCBP4 | PCGF2 | PCGF6 |
| PCL2 | PCNA | ||
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