| Cat.No.: | BSM-0107 |
| Product Name: | CUDC-101 |
| CAS No.: | 1012054-59-9 |
| Figure: |
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| Synonyms: | 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide |
| Description: | A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2 (IC50 = 4.4 nM, 2.4 nM and 15.7 nM respectively). It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors. |
| Appearance: | White solid |
| Molecular Weight: | 434.49 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | HDACs and receptor tyrosine kinases |
| Molecular Formula: | C24H26N4O4 |
| MDL Number: | MFCD15528940 |
| Solubility: | DMSO |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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