Cat.No.: | BSM-0101 |
Product Name: | Chidamide |
CAS No.: | 743420-02-2 |
Figure: | |
Synonyms: | N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide |
Description: | Chidamide is a histone deacetylase inhibitor which increases Histone H3 acetylation levels in LoVo and HT29 colon cancer cells at low concentrations (4 µM). Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells. |
Appearance: | White to off-white solid |
Molecular Weight: | 390.41 |
Purity: | ≥98% |
Storage: | -20°C |
Targets: | Histone deacetylase |
Molecular Formula: | C22H19FN4O2 |
MDL Number: | MFCD00133163 |
Solubility: | DMSO |
Shipping Conditions: | Gel Pack |
Warning: | For Research Use Only! Not For Use in Humans. |
Product Types | ||
◆ Extracts & Lysates | ||
EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
◆ Bioactive Small Molecules | ||
BSM-0007 | Tubacin | Inquiry |
Related Gene / Proteins | |||
HDAC | HDAC1 | HDAC10 | HDAC11 |
HDAC2 | HDAC3 | hdac4 | hdac5 |
HDAC6 | hdac7 | HDAC8 | hdac9 |
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