| Cat.No.: | BSM-0092 |
| Product Name: | BRD4770 |
| CAS No.: | 1374601-40-7 |
| Figure: |
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| Synonyms: | Methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate |
| Description: | BRD4770 is a selective inhibitor of the histone methyltransferase G9a (also named euchromatin histone methyltransferase 2 (EHMT2). BRD4770 blocks lysine residue 9 methylation of histone H3 without inducing apoptosis. In addition, it induces senescence, and inhibits both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1. |
| Appearance: | White to off-white solid |
| Molecular Weight: | 413.47 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | Histone methyltransferase G9a |
| Molecular Formula: | C₂₅H₂₃N₃O₃ |
| MDL Number: | MFCD02062139 |
| Solubility: | DMSO(10 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0025 | BIX01294 (hydrochloride hydrate) | Inquiry |
| BSM-0026 | UNC0224 | Inquiry |
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Cell Lines | ||
| CL-0059 | Human EHMT1 Knockout Cell Line 7bp deletion | Inquiry |
| CL-0060 | Human EHMT2 Knockout Cell Line 34bp deletion | Inquiry |
| Related Gene / Proteins | |||
| EHD2 | EHMT1 | EHMT2 | |
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