| Cat.No.: | BSM-0083 |
| Product Name: | Baricitinib |
| CAS No.: | 1187594-09-7 |
| Figure: |
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| Synonyms: | 2-[1-Ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile; INCB 028050;LY 3009104;INCB028050;LY3009104;LY-3009104;INCB-028050 |
| Description: | Baricitinib is a selective JAK1 and JAK2 inhibitor with IC₅₀ values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10-fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and Chk2. |
| Appearance: | White to off-white solid |
| Molecular Weight: | 371.42 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | JAK1 and JAK2 |
| Molecular Formula: | C₁₆H₁₇N₇O₂S |
| MDL Number: | MFCD16038904 |
| Solubility: | DMSO (>50 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0002 | AT9283 | Inquiry |
| ◆ Cell Lines | ||
| CL-0017 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| CL-0081 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0079 | JARID2 Polyclonal Antibody | Inquiry |
| EAb-0080 | JARID1C Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JADE1 | JAK | JAK1 | JAK2 |
| JAK3 | JAKMIP1 | JARID | JARID1 |
| JARID1A | JARID1B | JARID1C | JARID2 |
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