| Cat.No.: | BSM-0055 |
| Product Name: | (-)-JQ1 |
| CAS No.: | 1268524-71-5 |
| Figure: |
-JQ1-1.jpg)
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| Synonyms: | t-Butyl-2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate |
| Product Overview: | A negative control for (+)-JQ1 |
| Description: | (-)-JQ1 is the inactive stereoisomer of the potent, cell-permeable, small molecule bromodomain inhibitor (+)-JQ1 that competitively binds to acetyl-lysine recognition motifs. (-)-JQ1 enantiomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively. |
| Appearance: | Off-white solid |
| Molecular Weight: | 456.99 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Molecular Formula: | C23H25ClN4O2S |
| MDL Number: | MFCD00075940 |
| Solubility: | DMSO (~10 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
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