Cat.No.: | BSM-0046 |
Product Name: | RVX-208 |
CAS No.: | 1044870-39-4 |
Figure: |
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Synonyms: | 2-{4-(2-hydroxyethoxy)-3,5-dimethylphenyl}-5,7-dimethoxy-4(3H)-quinazolinone |
Description: | RVX-208 is a potent BET bromodomain antagonist with (IC50 = 0.51 µM for BD2) with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis. |
Appearance: | White powder. |
Molecular Weight: | 370.4 |
Purity: | >98% (TLC); NMR (Conforms) |
Storage: | Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month. |
Targets: | BET Bromodomain |
Molecular Formula: | C20H22N2O5 |
Solubility: | Dissolved in DMSO (75 mg/ml); Ethanol (4 mg/ml). |
Warning: | For Research Use Only! Not For Use in Humans. |
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