| Cat.No.: | EKIT-0582 |
| Product Name: | 5-hmC methylation kit |
| Size: | 50 tests |
| Product Overview: | Detect 5-hydroxymethylcytosine using a robust glucosylation method |
| Description: | The 5-hmC methylation kit allows for sequence specific detection of 5-hydroxymethylcytosine within DNA using a simple and efficient glucosylation reaction procedure. |
| Background: | 5-Hydroxymethylcytosine (5hmC), also known as the “6th base”, is a newly discovered epigenetic modification. Although it was first identified in bacteriophages, its role was thought to be limited to protecting the phage genome from host induced restriction endonucleases. Interestingly, 5-hydroxymethylcytosine has recently been found in embryonic stem cells, the brain, as well as numerous other organs. Even though its presence has been confirmed, its biological role remains elusive. It has been proposed that 5-hydroxymethylcytosine may play a role in DNA demethylation (5-methylcytosine) or be involved in another layer of gene expression regulation. |
| Kit Components: | 5-hmC Glucosyltransferase (5-hmC), 10X 5-hmC Reaction buffer, 10X UDPG (uridine diphosphoglucose), MspI restriction enzyme, 5-hmC Control DNA, qPCR Primer 1, qPCR Primer 2 and 5-DNA clean up concentrator kit |
| Storage: | -20°C |
| Warning: | For research use only, not for diagnostic use. |
| Product Types | ||
| ◆ Research Kits | ||
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USA
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