| Cat.No.: | EKIT-0545 |
| Product Name: | P300 Chemiluminescent Assay Kit |
| Size: | 96 reactions |
| Description: | The p300 Chemiluminescent Assay Kit is an enzyme-linked immunosorbent assay (ELISA) designed to screen for inhibitors of p300 or to measure histone acetyltransferase (HAT) activity for screening and profiling applications. Histone acetyltransferase p300 (also known as KAT3B) is involved in various cellular events, and its dysfunction is linked to a number of human diseases including Parkinson’s, Huntington’s, and Alzheimer’s diseases. The P300 Chemiluminescent Assay Kit is based on the p300 enzyme transferring an acetyl group from an acetyl donor (acetyl CoA) to a histone substrate. The acetylated histone is recognized by a highly specific primary antibody, followed by an HRP-labeled secondary antibody. The chemiluminescence produced by HRP can be measured using a chemiluminescence reader. |
| Applications: | For studying enzyme activity and screening small molecular inhibitors for drug discovery and HTS applications. |
| Kit Components: | The p300 Chemiluminescent Assay Kit comes in a convenient format, with Histone peptide, a 96-well plate precoated with Neutravidin and histone peptide, and all the reagents necessary for 96 chemiluminescent P300 activity measurements. In addition, the kit |
| Warning: | For research use only, not for diagnostic use. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0038 | CTPB | Inquiry |
| BSM-0073 | Anacardic Acid | Inquiry |
| BSM-0094 | C646 | Inquiry |
| BSM-0108 | Curcumin, Curcuma longa (High Purity) | Inquiry |
| ◆ Cell Lines | ||
| CL-0061 | Human EP300 Knockout Cell Line 13bp deletion | Inquiry |
| Related Gene / Proteins | |||
| EP300 | EPC1 | ||
USA
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