PRMT5 Homogeneous Assay Kit

Cat.No.:	EKIT-0486
Product Name:	PRMT5 Homogeneous Assay Kit
Size:	384 reactions
Description:	The PRMT5 Homogeneous Assay Kit is designed to measure PRMT5 activity for screening and profiling applications. PRMT5 is a histone methyltransferase that exhibits methylation activity toward H4-R3. The key to the PRMT5 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing PRMT5 enzyme is incubated with the biotinylated substrate for two hours. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.
Background:	PRMT5 is a histone methyltransferase that exhibits methylation activity toward H4-R3.
Applications:	For studying enzyme kinetics and HTS applications.
Kit Components:	The PRMT5 Homogeneous Assay Kit comes in a convenient AlphaLISA format, with biotinylated histone H4 peptide substrate, primary antibody, methylation assay buffer, and purified PRMT5 for 384 enzyme reactions.
Warning:	For research use only, not for diagnostic use.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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