KAT8 (MYST1) protein-GST fusion


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Cat.No.:  PE-3839
Product Name:  KAT8 (MYST1) protein-GST fusion
Description:  KAT8 (MYST1) recombinant protein-GST fusion protein. Recombinant human KAT8 (2-467; contains the catalytic domain) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein.
Background:  KAT8 (MYST1) or MYST histone acetyltransferase 1 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. MYST1 have a chromodomain that involved in protein-protein interactions and targeting transcriptional regulators to chromatin. MYST histone acetyltransferase 1 is also involved in ATM function. KAT8 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, and PKA/PKC Pathway research.
Applications:  Suitable for use in Western Blot.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid (sterile filtered)
Molecular Weight:  ~83kDa
Purity:  The purity was determined to be >80% by densitometry.
Species:  Human
Formulation:  50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Alternative Names:  KAT8, MYST1, hMOF, MOF, FLJ14040, Histone acetyltransferase KAT8, EC 2.3.1.48, Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, hMOF
Tag:  GST
Expression System:  Sf9 Insect Cells
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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