| Cat.No.: | PE-3834 |
| Product Name: | SIRT3 (human), (recombinant) (His-tag) |
| Description: | Active SIRT3 (aa 102-399). Contains a N-terminal His-tag. |
| Background: | Sirtuins, which are NAD-dependent lysine deacetylases, have been implicated in the control of longevity in yeast and C. elegans and, in yeast, have been shown to be necessary for the longevity increase effected by caloric restriction. Human SIRT3, one of seven human sirtuins, has been assigned, along with SIRT1 and SIRT2, to the class I sirtuin homology group. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 32.7 kDa |
| Purity: | Partially purified by single-step affinity chromatography and gel filtration. |
| Formulation: | 25mM TRIS, pH 7.5, containing 100mM NaCl, 5mM DTT, and 10% glycerol. |
| Accession#: | Q9NTG7 |
| Alternative Names: | Sirtuin 3 |
| Tag: | His |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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