| Cat.No.: | PE-3833 |
| Product Name: | SIRT2 (human), (recombinant) (His-tag) |
| Description: | Contains a N-terminal His-tag. |
| Background: | Due to their roles in gene silencing, aging, and oxidative stress responses, the sirtuins (NAD. Like Sir2, human SIRT2 is a class I sirtuin, although not as closely related to Sir2 and human SIRT1 and its catalytic core has the same basic two-domain architecture and central groove as other sirtuinsand an interaction with the homeobox transcription factor HOXA10. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 43 kDa |
| Purity: | Purified by multi-step chromatography. |
| Formulation: | 25mM TRIS, pH 7.5, containing 100mM NaCl, 5mM DTT and 10% glycerol. |
| Accession#: | Q8IXJ6 |
| Alternative Names: | Sirtuin 2 |
| Tag: | His |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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