| Cat.No.: | PE-3802 |
| Product Name: | Human recombinant UBE2R1 (CDC34) |
| Background: | UBE2R1 is important in the control of cell cycle and DNA replication. In association with different E3 complexes, including SCF, it has been shown to target many different substrates for ubiquitination and degradation during cell division, signal transduction, and development. UBE2R1 substrates include B-Myb, Wee1, MyoD, ATF5, p27Xic1, and p27Kip1. Additionally, substrates such as p21Cip1, E2F, cyclin E, and cyclin D are putative substrates of UBE2R1 by virtue of their SCF requirement for proteolysis. This protein is useful for in vitro ubiquitinylation reactions. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 27.730 kDa with His Tag. |
| Purity: | Purity by SDS-PAGE ≥95% |
| Formulation: | 50 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol. |
| Accession#: | P49427 |
| Alternative Names: | Human recombinant UBE2R1 (CDC34), CDC-34, Ubiquitin-conjugating enzyme E2 R1, Ubiquitin-protein ligase R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, E2-CDC34, CDC34, EC 6.3.2.19, UBC3. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0026 | Human UBAP1 Knockout Cell Line | Inquiry |
| CL-0112 | Human CDKN1B Knockout Cell Line 10bp deletion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0118 | Recombinant Mouse CDK1 Cell Lysate | Inquiry |
| EL-0119 | Recombinant Human CDK1 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0162 | Synthetic Human Ubiquitin protein (Biotin) | Inquiry |
| Related Gene / Proteins | |||
| CD1D | CDA | CDC34 | CDK1 |
| CDK8 | CDK9 | CDKA1 | CDKN1B |
| CDX1 | CDY2A | CDYL | UB2D1 |
| UB2D2 | UB2D3 | UB2R1 | UBA1 |
| UBA5 | UBA7 | UBAP1 | UBB More > |
| UBC | UBC12 | Ubc13 | Ubc3B |
| UbcH1 | UbcH2 | UbcH3 | UbcH5a |
| UbcH5b | UbcH5c | UbcH8 | UBD |
| UBE1L | UBE2B | UBE2C | UBE2D1 |
| UBE2D3 | UBE2DNL | UBE2E1 | UBE2E2 |
| UBE2E3 | UBE2G1 | UBE2G2 | UBE2H |
| UBE2I | UBE2K | UBE2L3 | UBE2L6 |
| UBE2M | UBE2N | UBE2O | UBE2Q2 |
| UBE2R1 | UBE2R2 | UBE2T | UBE2V1 |
| UBE2V2 | UBE2W | UBE3A | Ube4a |
| Ubiquitin | UBL7 | Ubn1 | UBP5 |
| UBR2 | UBTD1 | UBTD2 | UBXN10 |
| UBXN2B | UBXN6 | UBXN8 | |
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