| Cat.No.: | PE-3754 |
| Product Name: | Human Recombinant DUSP3 |
| Background: | DUSP3 belongs to the dual specificity protein phosphatase subfamily which inactivates their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSP3 negatively regulate members of the mitogen-activated protein kinase superfamily that are related to cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues and displays activity both for tyrosine-protein phosphate and serine-protein phosphate, but exhibits a strong preference toward phosphotyrosines, specifically dephosphorylates and inactivates ERK1 and ERK2. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 22.6 kDa (205 aa, 1-185 aa + NT His-Tag) |
| Purity: | Purity by SDS-PAGE ≥95% |
| Formulation: | 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2 mM DTT and 0.15 M NaCl. |
| Accession#: | P51452 |
| Alternative Names: | Dual specificity protein phosphatase 3, VHR. |
| Expression System: | E. Coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0117 | DUB Inhibitor, PR-619 | Inquiry |
| ◆ Cell Lines | ||
| CL-0187 | Human DUSP3 Knockout Cell Line | Inquiry |
| CL-0203 | Human DUSP19 Knockout Cell Line | Inquiry |
| CL-0231 | Human DUSP18 Knockout Cell Line | Inquiry |
| CL-0232 | Human DUSP4 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| DUB | DUSP1 | DUSP10 | DUSP11 |
| DUSP12 | DUSP13 | DUSP14 | DUSP15 |
| DUSP16 | DUSP18 | DUSP19 | DUSP2 |
| DUSP21 | DUSP22 | DUSP23 | DUSP26 |
| DUSP28 | DUSP3 | DUSP4 | DUSP6 More > |
| DUSP7 | DUSP8 | ||
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