| Cat.No.: | PE-3742 |
| Product Name: | TRIM24 recombinant protein |
| Description: | Full length recombinant human N-terminal Flag tagged TRIM24 (Tripartite Motif Containing 24) protein, producedin SF9 insect cells. |
| Background: | TRIM24 (UniProt/Swiss-Prot entry O15164) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zincbinding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. It acts as a a transcriptional coactivatorthrough it’s interaction with several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors, andcoactivators thereby modulating the transcription of target genes. TRIM24 is thought to associate with chromatin. This associationdepends on histone H3 modifications with the highest affinity for histone H3 that is both unmodified at ‘Lys-4’ and acetylated at‘Lys-23’. Defects in TRIM24 cause thyroid papillary carcinoma. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Purity: | Purified using FPLC, >95% purity as determined by SDS-PAGE. |
| Species: | Human |
| Formulation: | 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 MNaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT. |
| Alternative Names: | TIF1A, TIF1, TF1A, HTIF1, RNF82, PTC6 |
| Tag: | FLAG |
| Expression System: | Sf9 Insect Cells |
| Concentrations: | 0.5 µg/µl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| BSM-0021 | PF-03814735 | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0107 | Recombinant Human TRIM68 293 Cell Lysate | Inquiry |
| EL-0109 | Recombinant Human TRIP4 Lysate | Inquiry |
| EL-0115 | Recombinant Human TRIM24 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| TRA2A | TRAF4 | TRAF5 | TRAF6 |
| TRAK2 | TRBP | TRDMT1 | TREX1 |
| TRF2 | TRIM11 | TRIM13 | TRIM16 |
| TRIM17 | TRIM2 | TRIM21 | trim24 |
| TRIM26 | TRIM28 | TRIM3 | TRIM33 More > |
| TRIM34 | TRIM35 | TRIM36 | TRIM37 |
| TRIM38 | TRIM39 | TRIM4 | TRIM5 |
| TRIM55 | TRIM6 | TRIM63 | TRIM66 |
| TRIM68 | TRIM8 | TRIM9 | TRIML1 |
| TRIP4 | Tristetraprolin | TRIT1 | TrkA |
| TRMT2A | TRMT44 | TRMT5 | TRMT6 |
| TROVE2 | TRUB2 | TRX1 | TRβ1 |
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