Recombinant PRDM9 (191-415) protein

Cat.No.:	PE-3691
Product Name:	Recombinant PRDM9 (191-415) protein
Product Overview:	Recombinant PRDM9 protein corresponding to amino acids 191-415 of human PRDM9 (accession number NP_064612.2) was expressed in E.coli cells with an N-terminal GST tag. The molecular weight of this protein is 52 kDa.
Background:	PRDM9 (PR Domain Containing 9) is a Histone methyltransferase that specifically trimethylates Lys-4 of histone H3 during meiotic prophase and is essential for proper meiotic progression. PRDM9 has the ability to mono- and dimethylate Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes during early meiotic prophase (By similarity).
Applications:	Suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
Storage:	Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:	Liquid
Species:	Human
Formulation:	25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10% glycerol and 0.5 mM TCEP.
Tag:	GST
Expression System:	E. coli
Warning:	This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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