| Cat.No.: | PE-3467 |
| Product Name: | Recombinant IRF3 protein |
| Product Overview: | Recombinant human IRF3 was expressed in a baculovirus expression system as the full length protein (accession number NP_001562.1) with an N-terminal FLAG-Tag. The molecular weight of the protein is of 50.2 kDa. The IRF3 protein is >90% pure by SDS-PAGE. |
| Background: | IRF3 (Interferon regulatory factor 3)is a member of the IRF family of transcription factors that include IRF1, IRF6 and IRF7. IRF3 that has been phosphorylated at serine/threonine forms a complex with CREBBP and translocates to the nucleus to activate transcription of interferon-induced genes. IRF3 plays a critical role in the innate immune response against DNA and RNA viruses. |
| Applications: | Useful for the study of protein-protein interaction, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | 25 mM HEPES pH 7.5, 300 mM NaCl, 5% glycerol, 0.04% Triton X-100, 0.2 mM TCEP. |
| Tag: | FLAG |
| Expression System: | Baculovirus |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-1945 | IRF-5 Polyclonal Antibody | Inquiry |
| EAb-1946 | IRF-4 Polyclonal Antibody | Inquiry |
| EAb-1947 | IRF-3 Polyclonal Antibody | Inquiry |
| EAb-1948 | IRF-2 Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2084 | Recombinant human PARP3/IRT1 protein | Inquiry |
| Related Gene / Proteins | |||
| IRF-2 | IRF-3 | IRF-4 | IRF-5 |
| IRT1 | |||
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