| Cat.No.: | PE-3460 |
| Product Name: | Recombinant MePCE protein |
| Product Overview: | Recombinant MEPCE protein was expressed in a baculovirus expression system as the full length protein (accession number NP_062552.2) with an N-terminal FLAG-Tag. The molecular weight of the protein is 75.6 kDa. |
| Background: | MEPCE (Methylphosphate Capping Enzyme), also called as BCDIN3 (Bicoid-Interacting Protein 3 Homolog), is a RNA methyltransferase. It’s a S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5-end of 7SK snRNA, leading to stabilize it. Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, MEPCE/BCDIN3, SART3 proteins and 7SK and U6 snRNAs. |
| Applications: | Suitable for use in binding assays, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | 25 mM HEPES-NaOH pH7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5 mM TCEP. |
| Tag: | FLAG |
| Expression System: | Baculovirus |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0043 | Recombinant Human MECP2 293 Cell Lysate | Inquiry |
| EL-0111 | Recombinant Human MEF2B Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0067 | MeCP2 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0109 | Human MECP2 Knockout Cell Line 1bp insertion | Inquiry |
| CL-0110 | Human MEN1 Knockout Cell Line 1bp insertion | Inquiry |
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