| Cat.No.: | PE-3450 |
| Product Name: | Recombinant METTL7B protein |
| Product Overview: | Recombinant METTL7B protein was expressed in a baculovirus expression system as the full length human protein (accession number NP_004681.1) with a C-terminal FLAG tag. The molecular weight of the protein is 29.5 kDa. |
| Background: | METTL7B (Methyltransferase-Like Protein 7B) was originally identified as a Golgi-associated methyltransferase and is S-adenosylmethionine-dependent. It is associated with a lot of diseases including Muscular Dystrophy, Congenital, Due To Integrin Alpha-7 Deficiency and Supraglottis Cancer. Previous work has shown that RhoBTB1 regulates the integrity of the Golgi complex through METTL7B. RhoBTB1 is required for expression of METTL7B and silencing of either protein leads to fragmentation of the Golgi. |
| Applications: | Suitable for use in binding assays, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5 mM TCEP. |
| Tag: | FLAG |
| Expression System: | Baculovirus |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0043 | Recombinant Human MECP2 293 Cell Lysate | Inquiry |
| EL-0111 | Recombinant Human MEF2B Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0067 | MeCP2 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0109 | Human MECP2 Knockout Cell Line 1bp insertion | Inquiry |
| CL-0110 | Human MEN1 Knockout Cell Line 1bp insertion | Inquiry |
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