| Cat.No.: | PE-3424 |
| Product Name: | Recombinant c-Myc protein |
| Product Overview: | Recombinant c-Myc was expressed in a bacterial system (accession number NM 002467) with an N-terminal His-Tag and purified by an affinity column in combination with FPLC chromatography. The purified recombinant protein is greater than 75% homogeneous and contains no detectable protease, DNase and RNase activity. |
| Background: | c-Myc (Myc) is a sequence specific DNA binding transcription factor that regulates gene expression, especially genes involved in cell division. Myc family members contain a basic Helix-Loop-Helix leucine zipper (bHLHZ) domain. Myc family proteins associated with thousands of genes, especially those involved in cell growth and proliferation. c-Myc serves as an integrator of signal transduction, linking extracellular signals to an acute cellular growth response. Mutations and overexpression of c-Myc are associated with cell proliferation and cancer. |
| Applications: | Suitable for DNA and protein-protein interaction assays. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | Dilution Buffer AM1 (20 mM Tris-Cl (pH 7.5), 20% glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA). |
| Tag: | His |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| ◆ Antibodies | ||
| EAb-1913 | c-Myc Polyclonal Antibody (65 kDa form) | Inquiry |
| EAb-1914 | c-Myc Monoclonal Antibody | Inquiry |
| EAb-1941 | c-Jun Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1983 | C-jun Protein | Inquiry |
| Related Gene / Proteins | |||
| c-Fos | c-Jun | c-MET | c-Myc |
| c-RET | |||
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