Recombinant PLZF protein


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Cat.No.:  PE-3405
Product Name:  Recombinant PLZF protein
Product Overview:  Recombinant human PLZF was expressed in a baculovirus expression system as the full length protein (accession number NP_005997.2) with an N-terminal FLAG-Tag. The molecular weight of the protein is of 77.3 kDa. The IRF3 protein is >85% pure by SDS-PAGE.
Background:  PLZF (Promyelocytic Leukemia Zinc-Finger protein, also known as ZBTB16) is a member of the POK (POZ and Krüppel) family of transcriptional repressors. PLZF is expressed in early, but not differentiated, hematopoietic cells and is required for spermatogonial stem cell maintenance. In addition, PLZF regulates genes involved in cellular proliferation and differentiation (cyclin A2, Myc and Hox genes) and targeted deletion of PLZF in mice results in limb and axial skeleton and limb deformations.
Applications:  Useful for the study of protein-protein interaction, screening inhibitors, and selectivity profiling.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Species:  Human
Formulation:  25 mM HEPES pH 7.5, 300 mM NaCl, 5% glycerol, 0.04% Triton X-100, 0.2 mM TCEP.
Tag:  FLAG
Expression System:  Baculovirus
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Product Types
◆ Bioactive Small Molecules
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◆ Proteins & Enzymes
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Related Gene / Proteins
PLC PLU1 PLZF

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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