| Cat.No.: | PE-3391 |
| Product Name: | Recombinant TBP protein |
| Product Overview: | Recombinant human TBP protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003185.1) with an N-terminal FLAG tag. The molecular weight of the protein is 39 kDa. |
| Background: | TBP (also known as TATA box binding protein, GTF2D, transcription initiation factor TFIID TBP subunit, TATA-binding factor, TF2D, TFIID or SCA17). RNA polymerase II is an enzyme found in eukaryotic cells composed of 12 subunits that catalyzes transcription of DNA. Transcription consists of three phases: initiation, elongation and termination. Transcription initiation involves TFIID, which is composed of TATA-binding protein (TBP) and TBP-associated factors (TAFs), as part of the RNA polymerase II pre-initiation complex (PIC). TBP binds to the TATA box sequence, which is located upstream of the transcription start site in some eukaryotic gene promoters, and helps position RNA polymerase II. TBP contains a string of glutamines at the N-terminus which affect DNA binding and the rate of transcription complex formation. TBP is also associated with RNA polymerase I and RNA polymerase III. |
| Applications: | Suitable for use in protein-protein interaction, in vitro transcription assay, binding assay. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | 25 mM HEPES-NaOH pH 7.5, 500 mM NaCl, 10% glycerol, 0.04% Triton X-100 and 0.5 mM TCEP. |
| Tag: | FLAG |
| Expression System: | Baculovirus |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0015 | Hesperadin | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1170 | Recombinant Chicken TBL1XR1 | Inquiry |
| PE-1171 | Recombinant Mouse TBL1XR1 Protein | Inquiry |
| PE-1172 | Recombinant Human TBL1XR1 Protein, His-tagged | Inquiry |
| ◆ Antibodies | ||
| EAb-2567 | KAT4/TBP Associated Factor 1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| TbAUK1 | TBL1XR1 | TBP | |
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