| Cat.No.: | PE-3171 |
| Product Name: | PB1-1 (GST) |
| Description: | Human recombinant PB1-1 bromodomain expressed as an N-terminal GST-fusion protein in E.coli. PB1, a chromatin targeting component of the PBAF chromatin-remodeling complex, comprises six tandem bromodomains. Mutations in PB1, including PB1-1 occur frequently in renal cancers. Among the acetylated lysines of histone N-terminal tails, PB1-1 binds preferentially to H3K14aC. Crystal structures of PB1-1, both in complex with H3K14Ac peptide and isolation have been determined. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 43.0 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM Tris HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10 % glycerol |
| Accession#: | NM_018313 |
| Tag: | GST |
| Expression System: | E. coli |
| Protein Length: | 23-156 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0114 | Human PBRM1 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1119 | Recombinant Zebrafish PBRM1L | Inquiry |
| PE-1695 | PB1 (BD4), His-tag | Inquiry |
| PE-1717 | PB1 (BD6), His-tag | Inquiry |
| ◆ Antibodies | ||
| EAb-1869 | PBX2 Monoclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| PB1 | PBI | PBRM1 | PBRM1L |
| PBX | PBX1b | PBX2 | |
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