| Cat.No.: | PE-3162 |
| Product Name: | BRWD1-2 (His) |
| Description: | Human recombinant BRWD1, bromodomain-2. Full-length BRWD1 comprises two tandem bromodomains and eight WD repeats. The mouse homolog has been shown to associate with the SWI/SNF chromatin remodeling complex component, BRG1, and, through a polyglutamine-rich domain, to possibly function as a transcriptional activator. Like the tandem-bromodomain containing BET-family member BRDT, mouse BRWD1 is required for spermiogenesis, but unlike BRDT, it is also required for female fertility. The crystal structure of bromodomain-2 of human BRWD1 has been determined. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 17.0 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM Tris/HCl, pH 7.5, 500 mM NaCl, 1.0 mM TCEP, 10% glycerol (v/v) |
| Accession#: | NM_018963 |
| Tag: | His |
| Protein Length: | 1310-1430 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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