| Cat.No.: | PE-3157 |
| Product Name: | CREBBP (His) |
| Description: | Human recombinant CREBBP bromodomain. CREBBP and the closely related p300 are major regulators of gene transcription (co-activators) and function as lysine acetyltransferases for histones (i.e. HATs) and for numerous other proteins (e.g. p53). Aside from the acetyllysine-binding bromodomain and the catalytic HAT domain, native CREBBP comprises multiple protein-protein interaction domains (3 Cys-His-rich (CH) domains, KIX domain, steroid receptor co-activator interaction domain (SID)) and also has E3 and E4 ubiquitin ligase activities. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 16.7 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM Tris/HCl, pH 7.5, 500 mM NaCl, 1.0 mM TCEP, 10% glycerol (v/v) |
| Accession#: | NM_004380 |
| Tag: | His |
| Protein Length: | 1081-1197 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0055 | Human CREBBP Knockout Cell Line 1bp insertion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0094 | C646 | Inquiry |
| BSM-0124 | EML-425 | Inquiry |
| BSM-0150 | I-CBP112 (Hydrochloride) | Inquiry |
| ◆ Research Kits | ||
| EKIT-0122 | CBP bromodomain TR-FRET Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| CREB | CREB3 | crebbp | CRISP1 |
| CRISP3 | CRP | ||
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