| Cat.No.: | PE-3114 |
| Product Name: | BAZ2B (GST) |
| Description: | Human recombinant BAZ2B bromodomain. In addition to a bromodomain, native BAZ2B comprises several other domains (DDT, PHD, MBD (methyl-CpG-binding domain)) that may interact with the DNA and histones of chromatin and its associated proteins, including chromatin remodeling complexes. The BAZ2B bromodomain binds various Lys(Ac) residues in singly acetylated histone peptide microarrays (histones H1.4, H2A, H2B, H3, H4) with binding to histone H3 K14(Ac) confirmed in solution by isothermal titration calorimetry (ITC). An allele of the BAZ2B locus shows an association with increased risk for sudden cardiac death. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 40.4 kDa |
| Species: | Human |
| Formulation: | Solution of purified recombinant protein in 50 mM HEPES, pH 7.0, 150 mM NaCl, 1 mM TCEP, 10 % glycerol |
| Accession#: | NM_013450 |
| Tag: | GST |
| Protein Length: | 2054-2168 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0024 | Human BAP1 Knockout Cell Line 109bp insertion | Inquiry |
| CL-0030 | Human BAZ1A Knockout Cell Line 11bp deletion | Inquiry |
| CL-0031 | Human BAZ1B Knockout Cell Line 10bp deletion | Inquiry |
| CL-0032 | Human BAZ2A Knockout Cell Line 16bp deletion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0032 | Recombinant Human BAZ2B Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| BAF53A | BAP1 | BAP18 | BARD1 |
| BarX2 | BASP1 | BATZFD | BAZ1A |
| BAZ1B | BAZ2 | ||
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