Cat.No.: | PE-3037 |
Product Name: | NSD2 (His) Methyltransferase |
Description: | NSD2 (His) is a SET-domain lysine methyltransferase that exerts regulatory effects primarily through methylation of H3K36, a mark associated with gene activation, NSD2 may also act as an H4K20 methyltransferase as part of a DNA damage response. Notable for its role in the genesis of t(4; 14) translocation-positive multiple myelomas, NSD2 is also overexpressed in a wide range of human cancers and is considered a promising target for the development of anti-cancer therapies. |
Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
Molecular Weight: | 155.5 kDa |
Species: | Human |
Formulation: | Solution of purified recombinant protein in 50 mM Tris/HCl pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v). |
Accession#: | NM_001042424 |
Tag: | His |
Protein Length: | 2-1365 (end) |
Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Product Types | ||
◆ Cell Lines | ||
CL-0113 | Human NSD1 Knockout Cell Line 4bp deletion | Inquiry |
◆ Research Kits | ||
EKIT-0287 | NSD1 Chemiluminescent Assay Kit | Inquiry |
EKIT-0494 | NSD3 Chemiluminescent Assay Kit | Inquiry |
EKIT-0498 | NSD3 Chemiluminescent Assay Kit | Inquiry |
EKIT-0502 | NSD2 Chemiluminescent Assay Kit | Inquiry |
Related Gene / Proteins | |||
nsd1 | NSD2 | NSD3 | NSMCE2 |
NSUN1 | NSUN2 | NSUN3 | NSUN4 |
NSUN5 | NSUN6 | NSUN7 |
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