Recombinant Human NASP protein


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Cat.No.:  PE-2931
Product Name:  Recombinant Human NASP protein
Background:  Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
Applications:  ELISA; Western blot
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl
Alternative Names:  5033430J04Rik/AI131596/AI317140
Tag:  GST
Amino Acid Sequence:  MFLLLLHLQIKWRATINLLSVTEDGLHFVEYYLNRIIHLDVDSEAKKLLG LGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLEL ARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDEEAREELREQVY DAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSAEEPQEK VDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGT DVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEVEAE SLDPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVT TEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSI ERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGAT EKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSV LENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKL GEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNS QYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPE IREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRK PTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDA VPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC
Sequence Similarities:  Belongs to the NASP family.Contains 3 TPR repeats.
Expression System:  Wheat germ
Post Translational Modifications:  Phosphorylated upon DNA damage, probably by ATM or ATR.
Protein Length:  Full length protein; 1 to 790
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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