| Cat.No.: | PE-2858 |
| Product Name: | Recombinant Human GliS2/NKL protein |
| Background: | Can act either as a transcription repressor or as a transcription activator, depending on the cell context. Represses the transcriptional activation mediated by CTNNB1 in the Wnt pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation. |
| Applications: | ELISA; Western blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl |
| Alternative Names: | FLJ38247/GLI similar 2/GLI-similar 2 |
| Tag: | GST |
| Amino Acid Sequence: | MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPG SPGSPPSGFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSP ERQGNGDLPPVPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFL TPPKDKCLSPDLPLPKQLVCRWAKCNQLFELLQDLVDHVNDYHVKPEKDA GYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENL KIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGC HKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSG AQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGP GLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGS VPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASS PEALAPGWVVIPPGSVLLKPAVVN |
| Sequence Similarities: | Belongs to the GLI C2H2-type zinc-finger protein family.Contains 5 C2H2-type zinc fingers. |
| Expression System: | Wheat germ |
| Post Translational Modifications: | C-terminus cleavage is induced by interaction with CTNND1 and enhanced by Src tyrosine kinase. |
| Protein Length: | Full length protein; 1 to 524 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0071 | Recombinant Human NKX3 293 Cell Lysate | Inquiry |
| EL-0091 | Recombinant Human NKX2-5 Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0192 | GLI1 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0408 | Thielavin B | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0743 | Recombinant Chicken NKX2-5 | Inquiry |
| Related Gene / Proteins | |||
| GLI1 | GLI4 | GLIS1 | GliS2 |
| Glucose-6-phosphatase | GLYR1 | NKL | NKX2-5 |
| NKX3 | |||
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