| Cat.No.: | PE-2853 |
| Product Name: | Recombinant Human THAP1 protein (denatured) |
| Background: | DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 28 kDa including tags |
| Purity: | > 85 % SDS-PAGE. |
| Species: | Human |
| Formulation: | pH: 8.00; Constituents: 12.01% Urea, 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 1.17% Sodium chloride |
| Accession#: | Q9NVV9 |
| Alternative Names: | 4833431A01Rik/DYT6/FLJ10477 |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFK PTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAI GLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQV EKLRKKLKTA QQRCRRQERQ LEKLKEVVHF QKEKDDVSER GYVILPNDYF EIVEVPA |
| Sequence Similarities: | Belongs to the THAP1 family.Contains 1 THAP-type zinc finger. |
| Expression System: | E. coli |
| Protein Length: | Full length protein; 1 to 213 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0189 | Human THBS3 Knockout Cell Line | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2128 | Recombinant Human THAP7 protein (denatured) | Inquiry |
| PE-2257 | Recombinant Human THAP7 protein | Inquiry |
| PE-2750 | Recombinant Human THAP8 protein | Inquiry |
| PE-2751 | Recombinant Human THAP6 protein | Inquiry |
| Related Gene / Proteins | |||
| THAP1 | THAP11 | THAP2 | THAP6 |
| THAP7 | THAP8 | THBS3 | THRβ |
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