Recombinant Human TCF7L1 protein


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Cat.No.:  PE-2754
Product Name:  Recombinant Human TCF7L1 protein
Background:  Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.
Applications:  ELISA; Western blot
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl
Alternative Names:  bHLHb21/HMG box transcription factor/HMG box transcription factor 3
Tag:  GST
Amino Acid Sequence:  PAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQ PPLLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKS
Sequence Similarities:  Belongs to the TCF/LEF family.Contains 1 HMG box DNA-binding domain.
Expression System:  Wheat germ
Protein Length:  Protein fragment; 489 to 586
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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