Cat.No.: | PE-2630 |
Product Name: | Recombinant Human HSF4 protein |
Background: | DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription. |
Applications: | ELISA; Western blot; SDS-PAGE |
Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
Appearance: | Liquid |
Molecular Weight: | 37 kDa including tags |
Species: | Human |
Formulation: | pH: 8.00; Constituents: 0.79% Tris HCl, 0.3% Glutathione |
Accession#: | Q9ULV5 |
Alternative Names: | Cataract, Marner/CTM/Heat shock factor protein 4 |
Amino Acid Sequence: | KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWR EVVTLRQSHGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSC |
Sequence Similarities: | Belongs to the HSF family. |
Expression System: | Wheat germ |
Post Translational Modifications: | Phosphorylated mainly on serine residues. Phosphorylation on Ser-298 promotes sumoylation on Lys-293.Isoform HSF4B is constitutively sumoylated. Sumoylation represses the transcriptional activity and is promoted by phosphorylation on Ser-298. HSFA is not sumoylated. |
Protein Length: | Protein fragment; 120 to 219 |
Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Product Types | ||
◆ Cell Lines | ||
CL-0027 | Human HSPBAP1 Knockout Cell Line | Inquiry |
◆ Bioactive Small Molecules | ||
BSM-0337 | BIIB021 | Inquiry |
◆ Antibodies | ||
EAb-1959 | HSC70 / HSP7C Monoclonal Antibody | Inquiry |
EAb-1960 | HSP72 Monoclonal Antibody | Inquiry |
◆ Proteins & Enzymes | ||
PE-2336 | Recombinant Human HSPBAP1 protein | Inquiry |
Related Gene / Proteins | |||
HSC70 | HSF4 | HSP72 | Hsp90 |
HSPBAP1 | hSSB1 |
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