Recombinant Human HSF4 protein


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Cat.No.:  PE-2630
Product Name:  Recombinant Human HSF4 protein
Background:  DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription.
Applications:  ELISA; Western blot; SDS-PAGE
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Molecular Weight:  37 kDa including tags
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.79% Tris HCl, 0.3% Glutathione
Accession#:  Q9ULV5
Alternative Names:  Cataract, Marner/CTM/Heat shock factor protein 4
Amino Acid Sequence:  KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWR EVVTLRQSHGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSC
Sequence Similarities:  Belongs to the HSF family.
Expression System:  Wheat germ
Post Translational Modifications:  Phosphorylated mainly on serine residues. Phosphorylation on Ser-298 promotes sumoylation on Lys-293.Isoform HSF4B is constitutively sumoylated. Sumoylation represses the transcriptional activity and is promoted by phosphorylation on Ser-298. HSFA is not sumoylated.
Protein Length:  Protein fragment; 120 to 219
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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