Recombinant Human RNA Helicase A protein


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Cat.No.:  PE-2605
Product Name:  Recombinant Human RNA Helicase A protein
Background:  Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Component of the CRD-mediated complex that promotes MYC mRNA stability.
Applications:  Western blot; ELISA; SDS-PAGE
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Molecular Weight:  36 kDa including tags
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.3% Glutathione, 0.79% Tris HCl
Accession#:  Q08211
Alternative Names:  ATP dependent RNA helicase A/ATP-dependent RNA helicase A/DDX 9
Amino Acid Sequence:  MGDVKNFLYAWCGKRKMTPTYEIRAVGNKNRQKFMCEVQVEGYNYTGMGN STNKKDAQSNAARDFVNYLVRINEIKSEEVPAFGVASPPP
Sequence Similarities:  Belongs to the DEAD box helicase family. DEAH subfamily.Contains 2 DRBM (double-stranded RNA-binding) domains.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain.
Expression System:  Wheat germ
Post Translational Modifications:  Methylated. HRMT1L2 mediated methylation of undefined Arg residues in the NTD is required for nuclear localization.May be phosphorylated by PRKDC/XRCC7. Phosphorylated upon DNA damage, probably by ATM or ATR.
Protein Length:  Protein fragment; 1 to 90
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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